- The Tightening serum for your skin, best when used with its complementary cream. Fluid and quickly absorbed, it reactivates the skin components responsible for firmness. Visibly younger skin that is firmer and smoother, redefined facial contours. 30 day intensive treatment. In the morning and evening, after cleansing and spraying on Lotion Yon-Ka, apply the Advanced Optimizer Serum and then the Advanced Optimizer Crème to the face and neck. After the 30 days, apply the duo in the morning or in the evening to the face and neck. Clinical tests conducted over 4 consecutive weeks on 20 women aged 33 to 65 presenting skin slackening issues: cutometer measurements, clinical evaluation under the supervision of dermatologists, satisfaction tests.